SCHEMBL28072452

SCHEMBL28072452

COC(=O)/C=C(/CCc1ccccc1[N+](=O)[O-])C(=O)OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
RAB9A P51151 2/20 0.46
POLB P06746 2/20 0.46
PTPN1 P18031 1/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
MAOB P27338 1/20 0.41
ALDH1A1 P00352 4/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA2 P00918 1/20 0.41
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
MMP13 P45452 1/20 0.41
TSHR P16473 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7060894 0.82 NPSR1 (0.54) MAPTNPSR1RAB9APOLBPTPN1
SCHEMBL18801901 0.78 LMNA (0.51) MAPTNPSR1RAB9APOLBPTPN1
SCHEMBL9900416 0.77 NPSR1 (0.51) MAPTNPSR1RAB9APOLBPTPN1
SCHEMBL7061549 0.76 NPSR1 (0.48) MAPTNPSR1RAB9APOLBPTPN1
SCHEMBL8869665 0.75 RAB9A (0.52) MAPTNPSR1RAB9APOLBPTPN1
SCHEMBL8869674 0.75 RAB9A (0.52) MAPTNPSR1RAB9APOLBPTPN1
SCHEMBL7633450 0.75 MEN1 (0.57) MAPTNPSR1RAB9APOLBPTPN1
SCHEMBL6949395 0.74 PTPN1 (0.48) MAPTNPSR1RAB9APOLBPTPN1
SCHEMBL1805971 0.73 RAB9A (0.64) MAPTNPSR1RAB9APOLBPTPN1
SCHEMBL1805977 0.73 RAB9A (0.64) MAPTNPSR1RAB9APOLBPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104557583-B A kind of method synthesizing γ-aminobutyric acid class chipal compounds 中山大学 2016-06-29 CN disclosed