Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GRK2 | P25098 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868879 | 0.93 | CA1 (0.60) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL8869757 | 0.91 | TSHR (0.60) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL8869090 | 0.89 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL7870511 | 0.89 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL8868984 | 0.87 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL8868339 | 0.87 | CA1 (0.61) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL8868897 | 0.86 | ALDH1A1 (0.56) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL8868858 | 0.86 | CA1 (0.56) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL9517098 | 0.86 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL8870568 | 0.85 | P4HTM (0.47) | ALDH1A1MEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |