Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869090 | 0.93 | ALDH1A1 (0.51) | P4HTMSMN1; SMN2HIF1ANPC1RAB9A | |
| SCHEMBL8869248 | 0.92 | P4HTM (0.47) | P4HTMCA1CA2CA5ACA7 | |
| SCHEMBL8869814 | 0.91 | P4HTM (0.48) | P4HTMCA1CA2CA5ACA7 | |
| SCHEMBL8868425 | 0.91 | P4HTM (0.53) | P4HTMSMN1; SMN2HIF1ANPC1RAB9A | |
| SCHEMBL8869732 | 0.91 | P4HTM (0.53) | P4HTMCA1CA2CA5ACA7 | |
| SCHEMBL8867758 | 0.91 | P4HTM (0.46) | P4HTMCA1CA2CA5ACA7 | |
| SCHEMBL8868789 | 0.90 | P4HTM (0.48) | P4HTMCA1CA2CA5ACA7 | |
| SCHEMBL9144421 | 0.90 | P4HTM (0.52) | P4HTMCA1CA2CA5ACA7 | |
| SCHEMBL8869118 | 0.90 | PTPN1 (0.51) | P4HTMSMN1; SMN2PPARAALDH1A1LMNA | |
| SCHEMBL8868481 | 0.89 | HDAC3 (0.51) | P4HTMCA1CA2CA5ACA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |