Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868734 | 0.91 | L3MBTL1 (0.55) | HDAC1P4HTMLMNABCL2BCL2L1 | |
| SCHEMBL8868396 | 0.91 | HDAC3 (0.54) | HDAC3HDAC1HDAC8HDAC4HDAC6 | |
| SCHEMBL8870040 | 0.90 | L3MBTL1 (0.48) | HDAC3HDAC1HDAC8HDAC4HDAC6 | |
| SCHEMBL8869178 | 0.89 | P4HTM (0.54) | P4HTMNPC1RAB9ALMNAPKM | |
| SCHEMBL8869871 | 0.89 | P4HTM (0.49) | P4HTMNPC1RAB9ALMNAKDM4E | |
| SCHEMBL9143209 | 0.88 | RAB9A (0.57) | HDAC3HDAC1HDAC8HDAC4HDAC6 | |
| SCHEMBL8868506 | 0.88 | P4HTM (0.51) | P4HTMPKMKDM4EBDKRB1KMT2A | |
| SCHEMBL7869467 | 0.87 | MEN1 (0.48) | P4HTMSCN3ANPC1RAB9ALMNA | |
| SCHEMBL8868915 | 0.87 | P4HTM (0.66) | P4HTMCA12CA1CA2CA5A | |
| SCHEMBL8870497 | 0.86 | P4HTM (0.49) | P4HTMLMNAPKMKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |