Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869156 | 0.96 | P4HTM (0.51) | CA2P4HTMEGFRKDM4ECA12 | |
| SCHEMBL8869547 | 0.91 | CA2 (0.52) | CA2P4HTML3MBTL1NAAAEGFR | |
| SCHEMBL8868527 | 0.91 | CA2 (0.52) | CA2P4HTML3MBTL1NAAAEGFR | |
| SCHEMBL9139174 | 0.91 | P4HTM (0.62) | CA2P4HTML3MBTL1NAAAEGFR | |
| SCHEMBL8869712 | 0.89 | CA2 (0.50) | CA2P4HTML3MBTL1NAAAEGFR | |
| SCHEMBL8868684 | 0.89 | P4HTM (0.47) | CA2P4HTML3MBTL1NAAASMPD1 | |
| SCHEMBL8868794 | 0.89 | CA2 (0.50) | CA2P4HTML3MBTL1NAAAEGFR | |
| SCHEMBL8869078 | 0.89 | P4HTM (0.53) | CA2P4HTMEGFRKDM4ECA12 | |
| SCHEMBL9136947 | 0.89 | CA2 (0.54) | CA2P4HTML3MBTL1NAAAEGFR | |
| SCHEMBL8869529 | 0.88 | CA2 (0.48) | CA2P4HTML3MBTL1NAAAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |