Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869333 | 0.96 | P4HTM (0.48) | CA2P4HTML3MBTL1HPGDNPC1 | |
| SCHEMBL8867931 | 0.93 | HPGD (0.51) | P4HTML3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL8869631 | 0.93 | P4HTM (0.53) | CA2P4HTML3MBTL1HPGDNPC1 | |
| SCHEMBL8869547 | 0.92 | CA2 (0.52) | CA2P4HTML3MBTL1HPGDNPC1 | |
| SCHEMBL8868013 | 0.90 | P4HTM (0.50) | CA2P4HTML3MBTL1HPGDNPC1 | |
| SCHEMBL8869667 | 0.90 | P4HTM (0.53) | CA2P4HTMHPGDNPC1RAB9A | |
| SCHEMBL8868196 | 0.90 | P4HTM (0.53) | CA2P4HTMHPGDNPC1RAB9A | |
| SCHEMBL8868549 | 0.90 | HPGD (0.51) | P4HTML3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL8869984 | 0.89 | CA2 (0.55) | CA2P4HTML3MBTL1NAAAEGFR | |
| SCHEMBL8869009 | 0.89 | HPGD (0.50) | P4HTML3MBTL1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |