Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 16/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.46 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018280 | 0.80 | P4HTM (1.00) | P4HTMKDM4EALKBH2ALKBH3 | |
| SCHEMBL9018463 | 0.79 | P4HTM (1.00) | P4HTMALKBH2 | |
| SCHEMBL9018415 | 0.78 | P4HTM (0.80) | P4HTMKDM4EMAPK1L3MBTL1 | |
| SCHEMBL9140037 | 0.78 | P4HTM (0.60) | P4HTMMEN1KMT2A | |
| SCHEMBL9142936 | 0.77 | P4HTM (0.55) | P4HTMKDM4EMAPK1L3MBTL1 | |
| SCHEMBL9018490 | 0.75 | P4HTM (0.71) | P4HTMMEN1KMT2A | |
| SCHEMBL8869543 | 0.75 | P4HTM (0.76) | P4HTMKDM4EMAPK1L3MBTL1ALKBH2 | |
| SCHEMBL9140644 | 0.75 | P4HTM (0.56) | P4HTMMEN1KMT2A | |
| SCHEMBL9018328 | 0.75 | P4HTM (1.00) | P4HTMKDM4EMAPK1L3MBTL1 | |
| SCHEMBL9018361 | 0.74 | P4HTM (0.77) | P4HTMMEN1AHRKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |