Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 9/20 | 0.71 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018396 | 0.88 | ALDH1A1 (0.61) | P4HTMMMP2SLC16A3ALDH1A1MEN1 | |
| SCHEMBL9018280 | 0.83 | P4HTM (1.00) | P4HTMSLC16A3ALDH1A1 | |
| SCHEMBL8869007 | 0.82 | POLB (0.59) | P4HTMMMP2SLC16A3ALDH1A1MEN1 | |
| SCHEMBL9018005 | 0.79 | ALDH1A1 (0.53) | P4HTMALDH1A1MEN1KMT2AGAA | |
| SCHEMBL7317448 | 0.78 | GAA (0.59) | MMP2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9018463 | 0.76 | P4HTM (1.00) | P4HTM | |
| SCHEMBL8870053 | 0.75 | P4HTM (0.66) | P4HTMMEN1KMT2A | |
| SCHEMBL2702246 | 0.74 | ALDH1A1 (0.76) | MMP2SLC16A3ALDH1A1MEN1KMT2A | |
| SCHEMBL30708093 | 0.74 | ALDH1A1 (0.76) | MMP2SLC16A3ALDH1A1MEN1KMT2A | |
| SCHEMBL9574747 | 0.74 | POLB (0.56) | P4HTMALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | claimed |