Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.62 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.54 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Pyrrolidone SCHEMBL9795967 | 0.88 | OR51E2 (0.62) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL17698402 | 0.87 | OR51E2 (0.75) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL2155488 | 0.85 | OR51E2 (0.71) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL27878798 | 0.84 | OR51E2 (0.79) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL3729403 | 0.83 | OR51E2 (0.68) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL27605240 | 0.83 | OR51E2 (0.68) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL1436788 | 0.82 | — | — | |
| 2-Pyrrolidone SCHEMBL27555931 | 0.81 | OR51E2 (0.65) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL27544296 | 0.81 | OR51E2 (0.65) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL28180524 | 0.81 | OR51E2 (0.65) | OR51E2CRBNFKBP5KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170204062-A1 | PROCESS FOR THE PREPARATION OF REGORAFENIB AND ITS CRYSTALLINE FORMS | SHILPA MEDICARE LIMITED (IN) | 2017-07-20 | — | — | US | claimed |
| EP-2833867-A1 | SOLID ORAL PHARMACEUTICAL COMPOSITIONS FOR ISOXAZOLINE COMPOUNDS | Intervet International B.V. (NL) | 2015-02-11 | — | — | EP | claimed |
| WO-2013150055-A1 | SOLID ORAL PHARMACEUTICAL COMPOSITIONS FOR ISOXAZOLINE COMPOUNDS | INTERVET INTERNATIONAL B.V. (NL) | 2013-10-10 | — | — | WO | claimed |
| US-20110088511-A1 | METHOD FOR PRODUCING ROD-SHAPED AND BRANCHED METALLIC NANO-STRUCTURES BY POLYOL COMPOUNDS | JALALEDIN GHANAVI | 2011-04-21 | — | — | US | claimed |
| CN-1013867-B | PHOTOSTABLE POLYPARA-PHENYL-DIFORMYL PARAPHENYL-DIAMINE FIBER AND ITS SYNTHESIS | UNIV CHINA TEXTILE (CN) | 1991-09-11 | — | — | CN | claimed |
| US-20200306836-A1 | METHODS FOR THE PRODUCTION OF SILVER NANOWIRES | BASF SE (DE) | 2020-10-01 | — | — | US | disclosed |
| CN-109628005-B | Wireless charging ultra-thin black covering film and preparation method thereof | 深圳市弘海电子材料技术有限公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-110139878-A | Method for making crosslinked polymer | 索尔维特殊聚合物意大利有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-104470852-B | The mixed-metal oxides of fluorinated ion-exchange polymer are used for as scavenger | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2019-07-16 | — | — | CN | disclosed |
| CN-109971340-A | A kind of antistatic antirust covers the preparation method of iron film | 常州市贝特织造有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-108137965-A | Emulsion composition for ink and water-based ink | 日本化药株式会社 | 2018-06-08 | — | — | CN | disclosed |
| US-20170355023-A1 | METHODS FOR THE PRODUCTION OF SILVER NANOWIRES | BASF SE (DE) | 2017-12-14 | — | — | US | disclosed |
| US-5096991-A | Monomer from dihydroxy aromatic compound and haloalkylsilanol, elasticity, strength | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-03-17 | — | — | US | disclosed |
| CN-1013867-B | PHOTOSTABLE POLYPARA-PHENYL-DIFORMYL PARAPHENYL-DIAMINE FIBER AND ITS SYNTHESIS | UNIV CHINA TEXTILE (CN) | 1991-09-11 | — | — | CN | disclosed |
| EP-0483143-A4 | MEMBRANE AFFINITY APPARATUS AND PURIFICATION METHODS RELATED THERETO. | SEPRACOR INC (US) | 1991-07-24 | — | — | EP | disclosed |
| WO-1990005018-A1 | MEMBRANE AFFINITY APPARATUS AND PURIFICATION METHODS RELATED THERETO | SEPRACOR, INC. (US) | 1990-05-17 | — | — | WO | disclosed |
| CN-1036965-A | HIGHLY SOLUBLE AROMATIC POLYIMIDES | DU PONT (US) | 1989-11-08 | — | — | CN | disclosed |
| CN-1036777-A | Photostabilization Fanglun 1414 and synthetic | UNIV CHINA TEXTILE (CN) | 1989-11-01 | — | — | CN | disclosed |
| US-4187365-A | FROM POLYISOCYANATE, FORMIC ACID, AND DICARBOXYLIC ANHYDRIDE CONTAINING ANOTHER ACID GROUP | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-05 | — | — | US | disclosed |
| US-4097538-A | TREATING WITH LIQUID AMMONIA | GENERAL ELECTRIC COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204062-A1 | PROCESS FOR THE PREPARATION OF REGORAFENIB AND ITS CRYSTALLINE FORMS | BRAF, ALK, NRAS | OR51E2 3520/4885CRBN 486/4885FKBP5 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.