Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.41 |
| ▸ | CCR3 | P51677 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870550 | 1.00 | CCKBR (0.44) | CCKBRCA12CA1CA2CA9 | |
| SCHEMBL8870823 | 0.92 | PPIB (0.42) | CCKBRCA12CA1CA2CA9 | |
| SCHEMBL8870825 | 0.92 | PPIB (0.42) | CCKBRCA12CA1CA2CA9 | |
| SCHEMBL8870831 | 0.92 | PPIB (0.42) | CCKBRCA12CA1CA2CA9 | |
| SCHEMBL8870350 | 0.90 | HPSE (0.47) | CCKBRPRMT3MMEACEUSP30 | |
| SCHEMBL8870354 | 0.90 | HPSE (0.47) | CCKBRPRMT3MMEACEUSP30 | |
| SCHEMBL8869881 | 0.85 | PPIB (0.42) | CCKBRCCR3HTR2AKMT2A | |
| SCHEMBL8870087 | 0.84 | MME (0.47) | CCKBRPRMT3MMEACE | |
| SCHEMBL8870920 | 0.84 | ALDH1A1 (0.44) | PRMT3MMEACEKMT2A | |
| SCHEMBL8870918 | 0.84 | ALDH1A1 (0.44) | PRMT3MMEACEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |