Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | FFAR2 | O15552 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871013 | 1.00 | HSD17B10 (0.57) | HSD17B10ACEFFAR2POLBGAA | |
| SCHEMBL11385050 | 0.88 | ACE (0.61) | HSD17B10ACEFFAR2POLBGAA | |
| SCHEMBL10939993 | 0.84 | ACE (0.57) | HSD17B10ACEFFAR2POLBGAA | |
| SCHEMBL10920568 | 0.84 | ACE (0.74) | HSD17B10ACEFFAR2POLBALDH1A1 | |
| SCHEMBL10920564 | 0.84 | ACE (0.74) | HSD17B10ACEFFAR2POLBALDH1A1 | |
| SCHEMBL11282508 | 0.84 | ACE (0.74) | HSD17B10ACEFFAR2POLBALDH1A1 | |
| SCHEMBL683641 | 0.83 | ACE (0.73) | HSD17B10ACEFFAR2POLBGAA | |
| SCHEMBL8860652 | 0.83 | ACE (0.56) | HSD17B10ACEFFAR2POLBALDH1A1 | |
| SCHEMBL8870553 | 0.83 | ACE (0.56) | HSD17B10ACEFFAR2POLBALDH1A1 | |
| SCHEMBL13091650 | 0.82 | HSD17B10 (0.54) | HSD17B10ACEFFAR2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |