Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.42 |
| ▸ | HTR2C | P28335 | 7/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870566 | 0.95 | PDE3B (0.41) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL7761660 | 0.80 | CXCR4 (0.44) | HTR1AHTR2CPDE3BPDE3ALMNA | |
| SCHEMBL8870103 | 0.79 | SIGMAR1 (0.53) | HTR1AHTR2C | |
| SCHEMBL8871094 | 0.78 | HTR1A (0.42) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL8870600 | 0.77 | HTR1A (0.54) | HTR1AHTR2CDRD2HTR2ATP53 | |
| SCHEMBL8869966 | 0.77 | HTR1A (0.53) | HTR1AHTR2CDRD2HTR2ATP53 | |
| SCHEMBL8870746 | 0.77 | HTR1A (0.53) | HTR1AHTR2CDRD2HTR2ATP53 | |
| SCHEMBL8870642 | 0.75 | SIGMAR1 (0.50) | HTR1AHTR2C | |
| SCHEMBL9437757 | 0.74 | HTR1A (0.48) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL6190040 | 0.72 | SPHK1 (0.42) | HTR1AHTR2CALDH1A1GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688811-A | PSYCHOLOGICAL DISORDERS; NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-11-18 | — | — | US | disclosed |