Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871833 | 0.93 | HTR1A (0.51) | HTR1ACYP3A4KMT2ATSHRPKM | |
| SCHEMBL8870963 | 0.77 | HTR1A (0.59) | HTR1ACYP3A4HSD17B10ALDH1A1HPGD | |
| SCHEMBL9275178 | 0.76 | HTR1A (0.60) | HTR1ACYP3A4HSD17B10ALDH1A1HPGD | |
| SCHEMBL8871066 | 0.73 | HTR1A (0.64) | HTR1ACYP3A4HSD17B10ALDH1A1HPGD | |
| SCHEMBL8424220 | 0.71 | KMT2A (0.67) | KMT2ATSHRPKMSMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL8870351 | 0.71 | HTR1A (0.53) | HTR1ACYP3A4SIGMAR1DRD2 | |
| SCHEMBL8871523 | 0.70 | HTR1A (0.59) | HTR1ACYP3A4HSD17B10ALDH1A1HPGD | |
| SCHEMBL8870113 | 0.70 | HTR1A (0.63) | HTR1ACYP3A4KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL281993 | 0.69 | SCN9A (0.56) | HTR1ACYP3A4KMT2ATSHRPKM | |
| Hydrochloric Acid SCHEMBL8871647 | 0.69 | HTR1A (0.66) | HTR1ACYP3A4HSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648359-A | ESCHSCHOLTZINE AND DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0663210-A2 | Tumor necrosis factor production inhibitors | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1995-07-19 | — | — | EP | disclosed |