SCHEMBL887136

SCHEMBL887136

O=C[C@@H]1CCC[C@H](C=O)C1

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 8/20 0.36
ADH1C P00326 6/20 0.36
ADH1B P00325 2/20 0.35
ADH7 P40394 2/20 0.35
ADH4 P08319 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL887171 1.00 ADH1A (0.36) ADH1AADH1CADH1BADH7ADH4
SCHEMBL887172 1.00 ADH1A (0.36) ADH1AADH1CADH1BADH7ADH4
SCHEMBL887170 1.00 ADH1A (0.36) ADH1AADH1CADH1BADH7ADH4
SCHEMBL2855078 1.00 ADH1A (0.36) ADH1AADH1CADH1BADH7ADH4
SCHEMBL28253445 0.94 ADH1A (0.33) ADH1AADH1CADH1BADH7ADH4
SCHEMBL1684034 0.90 ADH1A (0.39) ADH1AADH1CADH1BADH7ADH4
SCHEMBL2859214 0.90 ADH1A (0.39) ADH1AADH1CADH1BADH7ADH4
SCHEMBL1684031 0.90 ADH1A (0.39) ADH1AADH1CADH1BADH7ADH4
SCHEMBL1684030 0.90 ADH1A (0.39) ADH1AADH1CADH1BADH7ADH4
SCHEMBL1684033 0.90 ADH1A (0.39) ADH1AADH1CADH1BADH7ADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3388486-B1 A CROSSLINKABLE COMPOSITION AND METHOD OF PRODUCING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-06-02 EP claimed
EP-3387080-B1 CROSSLINKABLE COMPOSITION AND COATING MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2021-05-12 EP claimed
EP-3010948-B1 A CROSS-LINKABLE COATING COMPOSITION AND METHOD OF PRODUCING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-03-03 EP claimed
EP-2876137-B1 Binder compositions of aliphatic or cycloaliphatic dicarboxaldehydes and resorcinol ROHM & HAAS (US) 2019-08-07 EP claimed
WO-2019142208-A1 AMBIENT TEMPERATURE CURABLE NON-ISOCYANATE POLYHYDROXYALKYLURETHANE MOIETIES WITH ALDEHYDE CROSS LINKER Asian Paints Ltd. (IN) 2019-07-25 WO claimed
US-20190225835-A1 POLYPHENOL ALKOXYLATE CONTAINING BLENDS AND COATINGS RESINATE MATERIALS GROUP, INC. 2019-07-25 US claimed
EP-3510069-A2 POLYPHENOL ALKOXYLATE CONTAINING BLENDS AND COATINGS Resinate Materials Group, Inc. (US) 2019-07-17 EP claimed
US-10144846-B2 Cross-linkable coating composition and method of producing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-04 US claimed
US-20180312722-A1 CROSSLINKABLE COMPOSITION AND COATING MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-01 US claimed
US-10030104-B2 Ambient temperature curable isocyanate-free compositions for preparing crosslinked polyurethanes DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-24 US claimed
EP-2749596-A1 A crosslinkable composition and method of producing the same Dow Global Technologies LLC (US) 2014-07-02 EP claimed
EP-2749595-A1 A crosslinkable composition and method of producing the same Dow Global Technologies LLC (US) 2014-07-02 EP claimed
US-8653174-B2 Ambient temperature curable isocyanate-free compositions for preparing crosslinked polyurethanes DOW GLOBAL TECHNOLOGIES LLC (US) 2014-02-18 US claimed
US-20130172472-A1 CROSSLINKABLE COMPOSITION AND METHOD OF PRODUCING THE SAME ROHM AND HAAS COMPANY (US) 2013-07-04 US claimed
US-20130165581-A1 CROSSLINKABLE COMPOSITION AND METHOD OF PRODUCING THE SAME ROHM AND HAAS COMPANY (US) 2013-06-27 US claimed
EP-2200957-B1 HYDROGENATION OF ALICYCLIC DIALDEHYDES TO ALICYCLIC DIOLS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-12-26 EP claimed
US-8304583-B2 Hydrogenation of aliphatic dialdehydes to aliphatic diols DOW GLOBAL TECHNOLOGIES LLC 2012-11-06 US claimed
EP-2397506-A1 Ambient temperature curable isocyanate-free compositions for preparing crosslinked polyurethanes DOW GLOBAL TECHNOLOGIES INC. (US) 2011-12-21 EP claimed
US-20110098514-A1 HYDROGENATION OF ALIPHATIC DIALDEHYDES TO ALIPHATIC DIOLS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2011-04-28 US claimed
US-6252121-B1 SEPARATION OF CYCLIC REACTANTS, CORRESPONDING PRODUCTS, NONPOLAR SOLVENT, ORGANOPHOSPHORUS LIGANDS AND CATALYST COMPLEX MATERIALS FROM MULTIPHASE REACTION PRODUCT FLUID HAVING POLAR AND NONPOLAR PHASES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2001-06-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098514-A1 HYDROGENATION OF ALIPHATIC DIALDEHYDES TO ALIPHATIC DIOLS ADH1C, ADH1A, DHCR24 ADH1A 2/4885ADH1C 1/4885ADH1B 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.