Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394986 | 0.85 | KDM4E (0.39) | ALDH1A1LMNAGAAKDM4E | |
| SCHEMBL13952783 | 0.78 | ALDH1A1 (0.34) | ALDH1A1THRBMAPK1POLB | |
| SCHEMBL16381859 | 0.72 | ALDH1A1 (0.33) | ALDH1A1THRBMAPK1POLB | |
| SCHEMBL10339691 | 0.69 | — | — | |
| SCHEMBL979584 | 0.64 | — | — | |
| SCHEMBL12038673 | 0.64 | — | — | |
| SCHEMBL12038676 | 0.64 | — | — | |
| SCHEMBL14844413 | 0.63 | — | — | |
| SCHEMBL12908953 | 0.61 | LMNA (0.38) | ALDH1A1LMNAGAAKDM4E | |
| SCHEMBL13947321 | 0.61 | LMNA (0.38) | ALDH1A1LMNAGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9936701-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2018-04-10 | — | — | US | disclosed |
| US-9936701-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2018-04-10 | — | — | US | disclosed |
| US-9936701-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2018-04-10 | — | — | US | disclosed |
| EP-2993986-B1 | HERBICIDAL ISOXAZOLYL SUBSTITUTED PYRROLONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-10 | — | — | EP | disclosed |
| EP-2993986-A1 | HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2016-03-16 | — | — | EP | disclosed |
| US-20160066574-A1 | Herbicidal Compounds | SYNGENTA LIMITED (GB) | 2016-03-10 | — | — | US | disclosed |
| US-20160066574-A1 | Herbicidal Compounds | SYNGENTA LIMITED (GB) | 2016-03-10 | — | — | US | disclosed |
| US-20160066574-A1 | Herbicidal Compounds | SYNGENTA LIMITED (GB) | 2016-03-10 | — | — | US | disclosed |
| WO-2014180740-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-13 | — | — | WO | disclosed |
| US-5654444-A | Preparation of 5-hydroxy-4-methyl-2(5H)-furanone | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-05 | — | — | US | disclosed |
| EP-0735032-A2 | Method for preparing 5-hydroxy-4-methyl-2(5H)-furanone | BASF AKTIENGESELLSCHAFT (DE) | 1996-10-02 | — | — | EP | disclosed |
| EP-0039830-A1 | Process for the preparation of optically active compounds and their use in the preparation of vitamin E | BASF Aktiengesellschaft (DE) | 1981-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160066574-A1 | Herbicidal Compounds | CBR3, DDT, RDX | ALDH1A1 532/4885LMNA 4160/4885GAA 1371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.