Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 5/20 | 0.43 |
| ▸ | EDNRA | P25101 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879365 | 0.88 | EDNRB (0.48) | KMT2AALDH1A1POLBKDM4EEDNRB | |
| SCHEMBL9878688 | 0.87 | EDNRB (0.44) | KMT2AALDH1A1POLBEDNRBEDNRA | |
| SCHEMBL1578804 | 0.78 | KMT2A (0.69) | KMT2AALDH1A1POLBCYP1A2PTGS1 | |
| SCHEMBL12096276 | 0.77 | EDNRB (0.53) | KMT2AEDNRBEDNRA | |
| SCHEMBL9459527 | 0.77 | EDNRB (0.53) | KMT2AEDNRBEDNRA | |
| SCHEMBL9341854 | 0.74 | EDNRB (0.42) | KMT2AEDNRBEDNRAMEN1 | |
| SCHEMBL9340022 | 0.74 | CTSA (0.53) | KMT2AALDH1A1KDM4EEDNRBEDNRA | |
| SCHEMBL7936610 | 0.73 | KMT2A (0.43) | KMT2AEDNRBEDNRAMAPTTP53 | |
| SCHEMBL28833357 | 0.72 | KLK7 (0.62) | KMT2AALDH1A1POLBMAPTTP53 | |
| SCHEMBL8975752 | 0.72 | SLC6A3 (0.40) | KMT2AALDH1A1KDM4EEDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604181-A | Pyrimidine derivatives herbicides | AGREVO UK LIMITED (GB) | 1997-02-18 | — | — | US | disclosed |
| US-5502028-A | Herbicidal pyrimidinyl or triazinyl haloacetic acid derivatives | SCHERING AGROCHEMICALS LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |
| EP-0660829-A1 | PYRIMIDINE DERIVATIVE HERBICIDES | AgrEvo UK Limited (GB) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994005644-A1 | PYRIMIDINE DERIVATIVE HERBICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1994-03-17 | — | — | WO | disclosed |
| EP-0575404-A1 | HERBICIDES | AgrEvo UK Limited (GB) | 1993-12-29 | — | — | EP | disclosed |
| WO-1992016511-A1 | HERBICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |