SCHEMBL8975752

SCHEMBL8975752

COc1cc(OC)nc(C(F)c2ccccc2)n1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.40
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
RAB9A P51151 1/20 0.40
EDNRB P24530 6/20 0.39
EDNRA P25101 6/20 0.39
KDM4E B2RXH2 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HTT P42858 1/20 0.36
GRM4 Q14833 1/20 0.36
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8872551 0.79 SLC6A3 (0.40) SLC6A3NPC1ALDH1A1RAB9AEDNRB
SCHEMBL9879365 0.75 EDNRB (0.48) SLC6A3ALDH1A1EDNRBEDNRAKDM4E
SCHEMBL8871840 0.72 KMT2A (0.49) ALDH1A1EDNRBEDNRAKDM4EMAPT
SCHEMBL8975651 0.70 EDNRB (0.47) EDNRBEDNRALMNA
SCHEMBL2288861 0.70 NPC1 (0.35) NPC1ALDH1A1RAB9AEDNRBEDNRA
SCHEMBL30617053 0.69 DPP4 (0.38) SLC6A3ALDH1A1
SCHEMBL9878688 0.69 EDNRB (0.44) SLC6A3ALDH1A1EDNRBEDNRAL3MBTL1
SCHEMBL2201461 0.69 OPRM1 (0.41) SLC6A3MAPTKMT2ALMNASMN1; SMN2
SCHEMBL2286995 0.69 HSP90AA1 (0.37) NPC1ALDH1A1RAB9AKDM4ELMNA
SCHEMBL2286514 0.69 TDO2 (0.33) NPC1ALDH1A1RAB9AEDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5502028-A Herbicidal pyrimidinyl or triazinyl haloacetic acid derivatives SCHERING AGROCHEMICALS LIMITED (GB) 1996-03-26 US disclosed
EP-0575404-A1 HERBICIDES AgrEvo UK Limited (GB) 1993-12-29 EP disclosed
WO-1992016511-A1 HERBICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-10-01 WO disclosed