Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549788 | 1.00 | GRIN2B (0.54) | GRIN2BHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL8547747 | 0.93 | GRIN2B (0.54) | GRIN2BHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL8547953 | 0.93 | GRIN2B (0.54) | GRIN2BHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL8547562 | 0.92 | ACHE (0.49) | GRIN2BHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL8543338 | 0.88 | GRIN1 (0.64) | GRIN2BHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL8547760 | 0.88 | GRIN2B (0.47) | GRIN2BCARM1PRMT6ACHE | |
| SCHEMBL8542536 | 0.85 | GRIN1 (0.52) | GRIN2BDRD2DRD3GRIN1CARM1 | |
| SCHEMBL8543200 | 0.85 | GRIN1 (0.52) | GRIN2BDRD2DRD3GRIN1CARM1 | |
| SCHEMBL8547676 | 0.83 | GRIN2B (0.54) | GRIN2BHTR1ADRD2HTR2AGRIN1 | |
| SCHEMBL8873886 | 0.83 | GRIN2B (0.54) | GRIN2BHTR1ADRD2HTR2AGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698553-A | Benzylpiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-16 | — | — | US | disclosed |