Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.38 |
| ▸ | SMO | Q99835 | 2/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778679 | 0.83 | CYP1A2 (0.40) | PDE10ANPC1CYP1A2SMOL3MBTL1 | |
| SCHEMBL8779764 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8779853 | 0.77 | PDGFRB (0.37) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8778780 | 0.77 | TDP1 (0.43) | PDE10ASMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL8779812 | 0.76 | L3MBTL1 (0.46) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8779911 | 0.74 | L3MBTL1 (0.56) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8778766 | 0.74 | CYP1A2 (0.42) | PDE10AKDM4ECYP1A2TRPM8 | |
| SCHEMBL8779883 | 0.73 | SMN1; SMN2 (0.39) | PDE10ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL8779778 | 0.73 | ALDH1A1 (0.45) | PDE10ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL3787309 | 0.73 | ALDH1A1 (0.51) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | NAT1, NQO2, NOX1 | PDE10A 1335/4885SMN1; SMN2 3646/4885KDM4E 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.