Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227531 | 0.75 | CFTR (0.44) | ARMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL10589837 | 0.75 | KDM4E (0.39) | ARMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8991102 | 0.70 | DYRK1A (0.56) | MEN1KMT2ATSHRNPC1HTT | |
| SCHEMBL4226153 | 0.70 | DPP4 (0.58) | MEN1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL9120609 | 0.70 | AR (0.47) | ARMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8872265 | 0.70 | KDM4E (0.39) | KDM4ELMNA | |
| SCHEMBL9120983 | 0.67 | L3MBTL1 (0.31) | — | |
| SCHEMBL9157389 | 0.67 | KDM4E (0.51) | ARMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL12895968 | 0.67 | MEN1 (0.55) | ARMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL9564330 | 0.66 | MAPT (0.49) | MEN1KMT2AALDH1A1NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043503-C | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID CO (US) | 1999-06-02 | — | — | CN | disclosed |
| US-5702681-A | ADMINISTERING A NITROPYRROLE OR A PYRROLE CARBONITRILE COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| US-5665759-A | ADMINISTERING A NITROPYRROLE OR PYRROLE CARBONITRILE COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1997-09-09 | — | — | US | disclosed |
| CN-1029313-C | Preparation method of pyrrole carbonitrile and nitropyrrole | AMERICAN CYANAMID CO (US) | 1995-07-12 | — | — | CN | disclosed |
| EP-0372263-B1 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID CO (US) | 1995-02-15 | — | — | EP | disclosed |
| CN-1098590-A | The application of pyrrole carbonitrile and nitro-pyrrole | AMERICAN CYANAMID CO (US) | 1995-02-15 | — | — | CN | disclosed |
| US-5371239-A | Pyrrole nitrile or nitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0557732-A1 | Methods and compositions for protecting animals against attack and infestation by helminth, acarid and anthropod endo- and ectoparasites | AMERICAN CYANAMID COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5204332-A | PYRROLE CARBONITRILE AND NITROPYRROLE INSECTICIDAL AND ACARICIDAL AND MOLLUSCICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1993-04-20 | — | — | US | disclosed |
| US-5162308-A | Pyrrole carbonitrile and nitropyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| CN-1043317-A | Pyrrolonitrile and nitropyrrole insecticides, acaricides and molluscicides and processes for their preparation | AMERICAN CYANAMID CO (US) | 1990-06-27 | — | — | CN | disclosed |
| EP-0372263-A2 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |