Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 6/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871814 | 0.75 | MGLL (0.40) | MAPTNPSR1LMNAHTTHSD17B10 | |
| SCHEMBL8872033 | 0.68 | KDM4E (0.53) | MAPTLMNAGAAHSD17B10GSK3B | |
| SCHEMBL3993416 | 0.66 | MAPT (1.00) | MAPTNPSR1LMNAHTTGAA | |
| Acetic Acid SCHEMBL9244244 | 0.66 | GAA (0.33) | NPSR1LMNAGAAMEN1KMT2A | |
| SCHEMBL8871887 | 0.66 | AR (0.46) | MAPTNPSR1LMNAHTTGSK3B | |
| SCHEMBL138022 | 0.66 | GSK3B (0.57) | MAPTLMNAGSK3BRAB9ANPC1 | |
| SCHEMBL20547722 | 0.65 | GSK3B (0.59) | MAPTLMNAHTTHSD17B10GSK3B | |
| SCHEMBL4153053 | 0.65 | SMN1; SMN2 (0.46) | MAPTLMNAHTTGAAHSD17B10 | |
| SCHEMBL15340905 | 0.64 | KMT2A (0.64) | MAPTLMNAGAAGSK3BRAB9A | |
| SCHEMBL26708953 | 0.64 | CA12 (0.57) | MAPTLMNAHTTGAAGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557732-A1 | Methods and compositions for protecting animals against attack and infestation by helminth, acarid and anthropod endo- and ectoparasites | AMERICAN CYANAMID COMPANY (US) | 1993-09-01 | — | — | EP | claimed |