Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15203782 | 0.98 | CPN1 (0.48) | CPN1CPB2LTA4HSLC1A3SLC1A2 | |
| SCHEMBL19815424 | 0.89 | CPN1 (0.46) | CPN1CPB2LTA4HSLC1A3SLC1A2 | |
| SCHEMBL19815425 | 0.89 | CPN1 (0.46) | CPN1CPB2LTA4HSLC1A3SLC1A2 | |
| SCHEMBL13711847 | 0.87 | ATM (0.50) | CPN1CPB2LTA4HSLC1A3SLC1A2 | |
| SCHEMBL2856572 | 0.87 | MMP2 (0.50) | CPN1CPB2LTA4HSLC1A3SLC1A2 | |
| SCHEMBL2484332 | 0.87 | ATM (0.50) | CPN1CPB2LTA4HSLC1A3SLC1A2 | |
| SCHEMBL31109109 | 0.87 | LTA4H (0.48) | CPN1CPB2LTA4HSLC1A3SLC1A2 | |
| SCHEMBL9208253 | 0.87 | MMP2 (0.50) | CPN1CPB2LTA4HSLC1A3SLC1A2 | |
| SCHEMBL22341309 | 0.87 | CPN1 (0.44) | CPN1CPB2LTA4HSLC1A3SLC1A2 | |
| SCHEMBL13711848 | 0.87 | ATM (0.50) | CPN1CPB2LTA4HSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610177-A | Acylated amino acids as endothelin antagonists | WARNER-LAMBERT COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0353211-A1 | New compounds | Aktiebolaget Hässle (SE) | 1990-01-31 | — | — | EP | disclosed |