Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9123097 | 0.75 | ALDH1A1 (0.32) | KDM4EALDH1A1TDP1GAAHPGD | |
| SCHEMBL8872265 | 0.73 | KDM4E (0.39) | KDM4ELMNA | |
| SCHEMBL9121110 | 0.72 | KDM4E (0.33) | KDM4EALDH1A1HPGDHSD17B10 | |
| Acetic Acid SCHEMBL9244244 | 0.71 | GAA (0.33) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL22605349 | 0.71 | KDM4E (0.61) | KDM4EALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL9341363 | 0.69 | APOBEC3G (0.36) | KDM4EALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL23014869 | 0.68 | ALDH1A1 (0.57) | KDM4EALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL9472193 | 0.68 | HPGD (0.35) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL9471857 | 0.68 | ALDH1A1 (0.34) | KDM4EALDH1A1TDP1POLBMAPT | |
| SCHEMBL9564330 | 0.68 | MAPT (0.49) | KDM4EALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702681-A | ADMINISTERING A NITROPYRROLE OR A PYRROLE CARBONITRILE COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| US-5665759-A | ADMINISTERING A NITROPYRROLE OR PYRROLE CARBONITRILE COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0372263-B1 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID CO (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5371239-A | Pyrrole nitrile or nitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0557732-A1 | Methods and compositions for protecting animals against attack and infestation by helminth, acarid and anthropod endo- and ectoparasites | AMERICAN CYANAMID COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5204332-A | PYRROLE CARBONITRILE AND NITROPYRROLE INSECTICIDAL AND ACARICIDAL AND MOLLUSCICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1993-04-20 | — | — | US | disclosed |
| US-5162308-A | Pyrrole carbonitrile and nitropyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0372263-A2 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |