Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586329 | 0.85 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1TSHRRAB9AMEN1 | |
| SCHEMBL6340427 | 0.84 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1TSHRRAB9AMEN1 | |
| SCHEMBL7731752 | 0.83 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1TSHRRAB9AMEN1 | |
| SCHEMBL5692150 | 0.83 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1TSHRRAB9AMEN1 | |
| SCHEMBL74692 | 0.83 | CYP1A2 (0.62) | ALDH1A1L3MBTL1TSHRRAB9AMEN1 | |
| SCHEMBL159214 | 0.81 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1TSHRRAB9AMEN1 | |
| SCHEMBL4684936 | 0.81 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1TSHRRAB9AMEN1 | |
| Silver SCHEMBL887040 | 0.81 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1TSHRRAB9AMEN1 | |
| SCHEMBL258555 | 0.81 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1TSHRRAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL2530464 | 0.81 | CYP1A2 (0.60) | ALDH1A1L3MBTL1TSHRRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594145-A | Process for the preparation of 2(3H)-benzothiazolones | HOECHST AG (DE) | 1997-01-14 | — | — | US | disclosed |
| EP-0162776-A2 | Heterocyclic derivatives, process for their preparation and medicaments useful as aldose reductase inhibitors containing them | LABORATOIRES UPSA (FR) | 1985-11-27 | — | — | EP | disclosed |