Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871861 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL8873269 | 0.99 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL5931841 | 0.84 | MAPT (0.46) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL5931837 | 0.84 | MAPT (0.46) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL7820402 | 0.81 | CHRNB2 (0.36) | — | |
| SCHEMBL7820404 | 0.81 | CHRNB2 (0.36) | — | |
| SCHEMBL19382162 | 0.70 | MAPT (0.48) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL7254100 | 0.70 | MAPT (0.44) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL6381203 | 0.69 | MAPT (0.47) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL6381199 | 0.69 | MAPT (0.47) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612351-A | AZABICYCLIC DERIVATIVES OF 1,2,3-OXA(OR THIA)DIAZOLE | NOVO NORDISK A/S (DK) | 1997-03-18 | — | — | US | disclosed |