Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564333 | 0.78 | DYRK1A (0.44) | DYRK1AGRIA4LMNAKMT2A | |
| SCHEMBL8872484 | 0.72 | DYRK1A (0.41) | DYRK1AGRIA4 | |
| SCHEMBL9120401 | 0.71 | DYRK1A (0.32) | DYRK1ALMNAKMT2AAR | |
| SCHEMBL9328906 | 0.67 | ALDH1A1 (0.33) | KMT2AAR | |
| SCHEMBL9340178 | 0.66 | — | — | |
| SCHEMBL26194102 | 0.66 | AR (0.37) | AR | |
| SCHEMBL27343303 | 0.65 | KDM4E (0.37) | DYRK1ALMNAKMT2AAR | |
| SCHEMBL9330894 | 0.65 | ALDH1A1 (0.32) | KMT2AAR | |
| SCHEMBL8871883 | 0.64 | DYRK1A (0.39) | DYRK1AGRIA4KMT2A | |
| SCHEMBL25613942 | 0.63 | AR (0.42) | LMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702681-A | ADMINISTERING A NITROPYRROLE OR A PYRROLE CARBONITRILE COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| US-5665759-A | ADMINISTERING A NITROPYRROLE OR PYRROLE CARBONITRILE COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0372263-B1 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID CO (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5371239-A | Pyrrole nitrile or nitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0557732-A1 | Methods and compositions for protecting animals against attack and infestation by helminth, acarid and anthropod endo- and ectoparasites | AMERICAN CYANAMID COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5204332-A | PYRROLE CARBONITRILE AND NITROPYRROLE INSECTICIDAL AND ACARICIDAL AND MOLLUSCICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1993-04-20 | — | — | US | disclosed |
| US-5162308-A | Pyrrole carbonitrile and nitropyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0372263-A2 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |