SCHEMBL9330894

SCHEMBL9330894

N#Cc1c(C#N)c(C#N)c(C(F)(F)F)c(C#N)c1C#N

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
HPGD P15428 3/20 0.32
KDM4E B2RXH2 2/20 0.32
GLA P06280 2/20 0.32
GAA P10253 2/20 0.32
TP53 P04637 2/20 0.32
KIF11 P52732 1/20 0.31
AR P10275 1/20 0.31
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9328906 0.97 ALDH1A1 (0.33) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL25613932 0.78 AR (0.42) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL25778068 0.78 HTT (0.35) ALDH1A1HPGDKDM4EARMAPT
SCHEMBL27355186 0.78 NOTUM (0.31) AR
SCHEMBL25778072 0.78 HTT (0.33) ARMAPTMAPK1SMN1; SMN2
SCHEMBL25613942 0.78 AR (0.42) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL9328654 0.77 MEN1 (0.33) ALDH1A1HPGDTP53MEN1CYP3A4
SCHEMBL25983363 0.76 KDM4E (0.47) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL9330078 0.75 TSHR (0.32) KMT2ASMN1; SMN2
SCHEMBL25986464 0.73 KCNMA1 (0.33) ALDH1A1HPGDKDM4EGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459196-B1 Fluoromethylated polycyanobenzenes, their addition compounds with alkalicyanides, process for their preparation and utilisation of the fluoromethylated polycyanobenzenes BAYER AG (DE) 1994-03-30 EP disclosed
US-5175336-A For detection of anions by visible coloration or fluorescence BAYER AKTIENGESELLSCHAFT (DE) 1992-12-29 US disclosed
EP-0459196-A1 Fluoromethylated polycyanobenzenes, their addition compounds with alkalicyanides, process for their preparation and utilisation of the fluoromethylated polycyanobenzenes BAYER AG (DE) 1991-12-04 EP disclosed