SCHEMBL8872437

SCHEMBL8872437

CC(C)(C)c1ccc(S)c(S)c1.[Ni]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
TSHR P16473 1/20 0.40
KIF11 P52732 5/20 0.39
LMNA P02545 1/20 0.39
TYR P14679 1/20 0.39
NPC1 O15118 1/20 0.38
PLA2G1B P04054 1/20 0.38
NFKB1 P19838 1/20 0.38
CASP3 P42574 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL179803 0.97 ALDH1A1 (0.46) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL29403104 0.97 ALDH1A1 (0.46) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL8469125 0.80 CYP1A2 (0.36) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL1843380 0.80 TSHR (0.46) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL7287002 0.78 TSHR (0.44) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL29529119 0.78 ALDH1A1 (0.43) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL20331 0.78 TSHR (0.44) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL7086864 0.78 ALDH1A1 (0.43) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL7286991 0.78 TSHR (0.44) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL9292631 0.78 ALDH1A1 (0.43) ALDH1A1HPGDALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2461353-B1 CMP POLISHING PAD AND METHOD FOR MANUFACTURING SAME UNIV SOGANG IND UNIV COOP FOUN (KR) 2015-09-09 EP disclosed
US-20120184194-A1 CMP POLISHING PAD AND METHOD FOR MANUFACTURING SAME Industry-University Cooperation Foundation Sogang University (KR) 2012-07-19 US disclosed
EP-2461353-A2 CMP POLISHING PAD AND METHOD FOR MANUFACTURING SAME Industry-University Cooperation Foundation Sogang University (KR) 2012-06-06 EP disclosed
US-5612279-A REVERSIBILITY NIPPON PAPER INDUSTRIES, LTD. (JP) 1997-03-18 US disclosed
US-5470816-A Urea developers NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1995-11-28 US disclosed