Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843380 | 0.83 | TSHR (0.46) | TSHRALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL24423316 | 0.82 | ESR1 (0.48) | TSHRALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL11157398 | 0.81 | PDE2A (0.42) | TSHRALDH1A1POLBMAPTMEN1 | |
| SCHEMBL7287002 | 0.81 | TSHR (0.44) | TSHRALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL7286991 | 0.81 | TSHR (0.44) | TSHRALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL179803 | 0.80 | ALDH1A1 (0.46) | TSHRALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL29403104 | 0.80 | ALDH1A1 (0.46) | TSHRALDH1A1HPGDALOX15HSD17B10 | |
| Acetonitrile SCHEMBL6325144 | 0.80 | HPGD (0.35) | TSHRALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL2009857 | 0.79 | TSHR (0.52) | TSHRALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL29498849 | 0.79 | TSHR (0.52) | TSHRALDH1A1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12084457-B2 | Methods for the preparation of 1,3-benzodioxole heterocyclic compounds | UNION therapeutics A/S (DK) | 2024-09-10 | — | — | US | claimed |
| CN-109265499-B | Reduction dehalogenation method of organic halogenated compound | 华中科技大学 | 2020-10-02 | — | — | CN | claimed |
| WO-2011124190-A2 | METHOD OF PRODUCING 4-(2-(SUBSTITUTED)-1-(1-HYDROXYCYCLOHEXYL)ETHYL)PHENOLS BY O- DEMETHYLATION OF THEIR METHYLETHERS BY MEANS OF INODOROUS AROMATIC THIOLS | ZENTIVA, K.S. (CZ) | 2011-10-13 | — | — | WO | claimed |
| US-20090142692-A1 | LOW MOLECULAR WEIGHT LATEX AND TONER COMPOSITIONS COMPRISING THE SAME | XEROX CORPORATION (US) | 2009-06-04 | — | — | US | claimed |
| US-20060286476-A1 | manufactured under monomer-starved polymerization condition such as monomer feeding rate equal to or less than 0.516% per minute by weight of the monomer(s) to be fed; gloss, fusing performance, crease performance, stripping performance, document offset, vinyl offset, and parent charging etc. | XEROX CORPORATION | 2006-12-21 | — | — | US | claimed |
| US-6967247-B2 | Deprotection of phosphorus in oligonucleotide synthesis | ISIS PHARMACEUTICALS, INC. (US) | 2005-11-22 | — | — | US | claimed |
| WO-2004020477-A1 | AQUEOUS POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF, ESPECIALLY IN ANTI-CORROSION COATINGS | CELANESE EMULSIONS GMBH (DE) | 2004-03-11 | — | — | WO | claimed |
| US-20040024194-A1 | Deprotection of phosphorus in oligonucleotide synthesis | ISIS PHARMACEUTICALS, INC. | 2004-02-05 | — | — | US | claimed |
| WO-2004009612-A1 | DEPROTECTION OF PHOSPHORUS IN OLIGONUCLEOTIDE SYNTHESIS | ISIS PHARMACEUTICALS, INC. (US) | 2004-01-29 | — | — | WO | claimed |
| US-6503680-B1 | Latex processes | XEROX CORPORATION | 2003-01-07 | — | — | US | claimed |
| US-6447974-B1 | SEMICONTINUOUS EMULSION POLYMERIZATION PROCESS FOR PREPARING TONER PARTICLES WHEREIN THE LATEX IS FORMED BY EMULSION POLYMERIZATION IN THE PRESENCE OF AN ANIONIC SURFACTANT; EXCELLENT IMAGE UNIFORMITY | XEROX CORPORATION | 2002-09-10 | — | — | US | claimed |
| US-6376630-B1 | CONTAINING (DI)CYCLOPENTADIENE AND VINYL AROMATIC COMPOUND | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | claimed |
| US-6040388-A | HYDROGENATED PRODUCT OF A COPOLYMER OF CYCLOPENTADIENE AND/OR DICYCLOPENTADIENE AND A VINYL-SUBSTITUTED AROMATIC COMPOUND. | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | claimed |
| US-5994547-A | Process for preparing benzo[b]thiophenes | ELI LILLY AND COMPANY (US) | 1999-11-30 | — | — | US | claimed |
| EP-0875511-A1 | Demethylation process for preparing benzo[b]thiophenes | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | claimed |
| EP-0711787-B1 | Process for preparing water-soluble polymers | HOECHST FRANCE (FR) | 1998-09-09 | — | — | EP | claimed |
| EP-0368697-B1 | 2-METHYL-5-T-BUTYL THIOPHENOL, ITS PREPARATION AND USE | SOCIETE FRANCAISE HOECHST (FR) | 1992-09-16 | — | — | EP | claimed |
| US-4948827-A | STABILIZER FOR VINYL CHLORIDE POLYMERS, CHAIN TRANSFER AGENTS AND PEPTIZERS | SOCIETE FRANCAISE HOECHST (FR) | 1990-08-14 | — | — | US | claimed |
| JP-11005789-A | — | — | None | — | — | JP | disclosed |
| EP-0368697-A1 | 2-Methyl-5-t-butyl thiophenol, its preparation and use | SOCIETE FRANCAISE HOECHST (FR) | 1990-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12084457-B2 | Methods for the preparation of 1,3-benzodioxole heterocyclic compounds | PDE4B, PDE4A, PDE4C | TSHR 3838/4885ALDH1A1 719/4885HPGD 89/4885 |
| US-20040024194-A1 | Deprotection of phosphorus in oligonucleotide synthesis | OR51E2, PNKP, RNGTT | TSHR 1151/4885ALDH1A1 2710/4885HPGD 4490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.