SCHEMBL887246

SCHEMBL887246

C=C(C)C(=O)OCC(=C)C(N)=O

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
TDP1 Q9NUW8 2/20 0.46
THRB P10828 1/20 0.44
ALDH1A1 P00352 2/20 0.41
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL8848233 0.88 TSHR (0.42) TSHRTDP1THRBALDH1A1
SCHEMBL2523421 0.82 TSHR (0.50) TSHRTDP1THRBALDH1A1POLB
SCHEMBL7776382 0.82 TDP1 (0.43) TSHRTDP1ALDH1A1ALOX15
SCHEMBL26661165 0.82 TSHR (0.50) TSHRTDP1THRBALDH1A1POLB
Hydrochloric Acid SCHEMBL27893796 0.80 TSHR (0.48) TSHRTDP1THRBALDH1A1POLB
SCHEMBL2401422 0.80 TSHR (0.48) TSHRTDP1THRBALDH1A1POLB
Urea SCHEMBL15263286 0.79 THRB (0.65) TSHRTDP1THRBALDH1A1POLB
SCHEMBL3818412 0.79 THRB (0.50) TSHRTDP1THRBALDH1A1POLB
Urea SCHEMBL28331735 0.77 THRB (0.57) TSHRTDP1THRBALDH1A1ALOX15
SCHEMBL28564447 0.77 THRB (0.52) TSHRTHRBALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108291111-B Crosslinkable compositions and coatings made therefrom 陶氏环球技术有限责任公司 2021-11-05 CN disclosed
EP-3387080-B1 CROSSLINKABLE COMPOSITION AND COATING MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2021-05-12 EP disclosed
CN-106008965-B Ambient temperature curable isocyanate-free compositions for preparing crosslinked polyurethanes 陶氏环球技术有限责任公司 2021-04-30 CN disclosed
US-20190105884-A1 COATED FILMS AND PACKAGES FORMED FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-11 US disclosed
EP-3464431-A1 COATED FILMS AND PACKAGES FORMED FROM SAME Dow Global Technologies LLC (US) 2019-04-10 EP disclosed
US-20180312722-A1 CROSSLINKABLE COMPOSITION AND COATING MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-01 US disclosed
EP-3387080-A1 CROSSLINKABLE COMPOSITION AND COATING MADE THEREFROM Dow Global Technologies LLC (US) 2018-10-17 EP disclosed
US-10030104-B2 Ambient temperature curable isocyanate-free compositions for preparing crosslinked polyurethanes DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-24 US disclosed
EP-3075755-B1 AMBIENT TEMPERATURE CURABLE ISOCYANATE-FREE COMPOSITIONS FOR PREPARING CROSSLINKED POLYURETHANES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-02-28 EP disclosed
WO-2017210087-A1 COATED FILMS AND PACKAGES FORMED FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2017-12-07 WO disclosed
US-9580622-B2 Crosslinkable composition, a method of making the same and a crosslinked composition produced therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-28 US disclosed
CN-106008965-A AMBIENT TEMPERATURE CURABLE ISOCYANATE-FREE COMPOSITIONS FOR PREPARING CROSSLINKED POLYURETHANES 陶氏环球技术有限责任公司 2016-10-12 CN disclosed
US-20160289386-A1 AMBIENT TEMPERATURE CURABLE ISOCYANATE-FREE COMPOSITIONS FOR PREPARING CROSSLINKED POLYURETHANES DOW GLOBAL TECHNOLOGIES LLC 2016-10-06 US disclosed
EP-3075755-A1 AMBIENT TEMPERATURE CURABLE ISOCYANATE-FREE COMPOSITIONS FOR PREPARING CROSSLINKED POLYURETHANES Dow Global Technologies LLC (US) 2016-10-05 EP disclosed
EP-2883894-B1 A crosslinkable composition, a method of making the same and a crosslinked composition produced therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2016-09-07 EP disclosed
US-20150166828-A1 Crosslinkable Composition, a Method of Making the Same and a Crosslinked Composition Produced Therefrom DOW GLOBAL TECHNOLOGIES LLC 2015-06-18 US disclosed
EP-2883894-A1 A crosslinkable composition, a method of making the same and a crosslinked composition produced therefrom Dow Global Technologies LLC (US) 2015-06-17 EP disclosed
US-8653174-B2 Ambient temperature curable isocyanate-free compositions for preparing crosslinked polyurethanes DOW GLOBAL TECHNOLOGIES LLC (US) 2014-02-18 US disclosed
US-20110313091-A1 AMBIENT TEMPERATURE CURABLE ISOCYANATE-FREE COMPOSITIONS FOR PREPARING CROSSLINKED POLYURETHANES DOW GLOBAL TECHNOLOGIES LLC (US) 2011-12-22 US disclosed
EP-2397506-A1 Ambient temperature curable isocyanate-free compositions for preparing crosslinked polyurethanes DOW GLOBAL TECHNOLOGIES INC. (US) 2011-12-21 EP disclosed