SCHEMBL7776382

SCHEMBL7776382

C=C(COC(C)=O)C(N)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.43
ALDH1A1 P00352 6/20 0.40
HSD17B10 Q99714 2/20 0.40
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 3/20 0.33
CHRM5 P08912 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
ALOX15 P16050 2/20 0.33
TSHR P16473 2/20 0.33
PGR P06401 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
HTR1A P08908 1/20 0.33
CHRNB2 P17787 1/20 0.33
TBXA2R P21731 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL887246 0.82 TSHR (0.47) TDP1ALDH1A1ALOX15TSHR
SCHEMBL11446032 0.80 ALDH1A1 (0.43) TDP1ALDH1A1HSD17B10LMNASMN1; SMN2
SCHEMBL28895438 0.79 MGAM (0.43) TDP1GAA
SCHEMBL352316 0.78 ALDH1A1 (0.42) TDP1ALDH1A1HSD17B10LMNASMN1; SMN2
SCHEMBL7768844 0.77 NAAA (0.38) TDP1ALDH1A1ALOX15GAABLM
SCHEMBL483086 0.76 ALDH1A1 (0.40) TDP1ALDH1A1HSD17B10LMNASMN1; SMN2
SCHEMBL27425209 0.76 TDP1 (0.33) TDP1ALOX15TSHR
SCHEMBL1000321 0.75
SCHEMBL28286108 0.74 HSD17B10 (0.44) TDP1ALDH1A1HSD17B10LMNASMN1; SMN2
SCHEMBL351718 0.74 ALDH1A1 (0.48) TDP1ALDH1A1HSD17B10LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1103698-C Lithographic form plate TORAY INDUSTRIES (JP) 2003-03-26 CN disclosed
EP-0755803-B1 LITHOGRAPHIC FORM PLATE TORAY INDUSTRIES (JP) 2001-07-25 EP disclosed
US-6093509-A NON-IMAGE AREA COMPRISE A HYDROPHILIC SWELLABLE LAYER WITH SPEACIFIC WATER ABSORBABILITY, MODULUS AND WATER SWELLING RATIO TORAY INDUSTRIES, INC. (JP) 2000-07-25 US disclosed
CN-1152278-A Lithographic form plate TORAY INDUSTRIES (JP) 1997-06-18 CN disclosed
EP-0755803-A1 LITHOGRAPHIC FORM PLATE TORAY INDUSTRIES, INC. (JP) 1997-01-29 EP disclosed