Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873865 | 0.91 | AGTR1 (0.47) | SLC6A3SLC6A4AGTR1AGTR2TLR8 | |
| SCHEMBL8874060 | 0.91 | SLC6A3 (0.48) | SLC6A3SLC6A4SLC6A2AGTR1AGTR2 | |
| SCHEMBL8873625 | 0.91 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2AGTR1AGTR2 | |
| SCHEMBL9414619 | 0.88 | MEN1 (0.38) | AGTR1POLB | |
| SCHEMBL8873335 | 0.86 | AGTR1 (0.47) | SLC6A3SLC6A4SLC6A2AGTR1AGTR2 | |
| SCHEMBL8872976 | 0.83 | AGTR1 (0.47) | SLC6A3SLC6A4AGTR1AGTR2ACHE | |
| SCHEMBL8872214 | 0.83 | AGTR1 (0.45) | SLC6A3AGTR1AGTR2TLR8ACHE | |
| SCHEMBL9279917 | 0.79 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9016524 | 0.78 | PPARG (0.41) | AGTR1ACHE | |
| SCHEMBL7388926 | 0.78 | F10 (0.38) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618969-A | Intermediates for imidazopyridines | EISAI CO., LTD. (JP) | 1997-04-08 | — | — | US | disclosed |
| US-5587504-A | Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates | EISAI CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |