Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249305 | 0.85 | LMNA (0.76) | LMNACYP3A4ACHEKMT2AMEN1 | |
| SCHEMBL17028900 | 0.85 | LMNA (0.76) | LMNACYP3A4ACHEKMT2AMEN1 | |
| SCHEMBL28032593 | 0.82 | LMNA (0.66) | LMNACYP3A4ACHEKMT2AMEN1 | |
| Ethylene SCHEMBL28866733 | 0.81 | LMNA (0.70) | LMNACYP3A4ACHEKMT2AMEN1 | |
| SCHEMBL13930374 | 0.79 | LMNA (0.68) | LMNACYP3A4ACHEKMT2AMEN1 | |
| SCHEMBL9512129 | 0.79 | MAPT (0.50) | LMNACYP3A4ACHEKMT2AMEN1 | |
| SCHEMBL4446422 | 0.78 | MAPT (0.67) | LMNACYP3A4ACHEALDH1A1MAPT | |
| SCHEMBL361383 | 0.78 | LMNA (0.66) | LMNACYP3A4ACHEKMT2AMEN1 | |
| SCHEMBL9769390 | 0.78 | LMNA (0.66) | LMNACYP3A4ACHEKMT2AMEN1 | |
| SCHEMBL280618 | 0.78 | LMNA (1.00) | LMNACYP3A4ACHEKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625077-A | 1,2-dioxetanes | TROPIX, INC. (US) | 1997-04-29 | — | — | US | disclosed |