SCHEMBL361383

SCHEMBL361383

COc1cccc(OC(C)=O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.66
CYP3A4 P08684 1/20 0.66
ALDH1A1 P00352 2/20 0.62
NPC1 O15118 1/20 0.62
TP53 P04637 1/20 0.62
HTT P42858 1/20 0.62
RAB9A P51151 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
ACHE P22303 1/20 0.59
CES2 O00748 1/20 0.57
CES1 P23141 1/20 0.57
PARP1 P09874 1/20 0.53
ESR1 P03372 1/20 0.53
ESR2 Q92731 1/20 0.53
GAPDH P04406 1/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
MTNR1A P48039 5/20 0.51
MTNR1B P49286 5/20 0.51
F2 P00734 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8218800 0.98 LMNA (0.63) LMNACYP3A4ALDH1A1NPC1TP53
SCHEMBL26009141 0.94 MTNR1B (0.59) LMNACYP3A4ALDH1A1NPC1TP53
SCHEMBL17028900 0.91 LMNA (0.76) LMNACYP3A4ALDH1A1NPC1TP53
SCHEMBL249305 0.91 LMNA (0.76) LMNACYP3A4ALDH1A1NPC1TP53
SCHEMBL26009136 0.90 LMNA (0.59) LMNACYP3A4ALDH1A1NPC1TP53
SCHEMBL9671485 0.88 LMNA (0.59) LMNACYP3A4ALDH1A1NPC1TP53
Ethylene SCHEMBL28866733 0.87 LMNA (0.70) LMNACYP3A4ALDH1A1NPC1TP53
SCHEMBL13930374 0.85 LMNA (0.68) LMNACYP3A4ALDH1A1ACHEMEN1
SCHEMBL30463307 0.85 CES2 (0.59) LMNAACHECES2CES1PARP1
SCHEMBL8048513 0.85 CES2 (0.59) LMNAACHECES2CES1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025243208-A2 PROCESS FOR THE PREPARATION AND/OR PURIFICATION OF POLYETHYLENE GLYCOL AND ITS DERIVATIVES, OBTAINED PRODUCT AND USES THEREOF HOVIONE - FARMACIÊNCIA, SA (PT) 2025-11-27 WO claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-5866608-A AROMATIC COMPOUNDS BIORESEARCH, INC. (US) 1999-02-02 US claimed
US-5637618-A PHENYL-CONTAINING COMPOUNDS (TASTANDS) TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE; FOODS; DRUGS; SWEETENERS; POTASSIUM CHLORIDE BIORESEARCH, INC. (US) 1997-06-10 US claimed
US-5631038-A COMPOUNDS (TASTANDS) TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE ARE ADDED TO FOODS CONTAINING SODIUM CHLORIDE BIORESEARCH, INC. (US) 1997-05-20 US claimed
EP-0661932-A4 SPECIFIC EATABLE TASTE MODIFIERS. BIORESEARCH INC (US) 1996-06-05 EP claimed
EP-0661932-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1995-07-12 EP claimed
WO-1993010677-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1993-06-10 WO claimed
EP-0027891-B1 AMMONIUM SALTS, A PROCESS FOR THE PREPARATION OF AMINES UNDERLYING THESE, AND COATING COMPOSITIONS ON THE BASIS OF MANUFACTURED POLYURETHANE OR EPOXY RESIN PRODUCTS WHICH CONTAIN THE AMMONIUM SALTS BAYER AG (DE) 1983-03-09 EP claimed
WO-2025243208-A2 PROCESS FOR THE PREPARATION AND/OR PURIFICATION OF POLYETHYLENE GLYCOL AND ITS DERIVATIVES, OBTAINED PRODUCT AND USES THEREOF HOVIONE - FARMACIÊNCIA, SA (PT) 2025-11-27 WO disclosed
WO-2025090480-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-05-01 WO disclosed
EP-4532484-A1 ROCK INHIBITORS AND USES THEREOF DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2025-04-09 EP disclosed
CN-119173509-A ROCK inhibitors and uses thereof 迪哲(江苏)医药股份有限公司 2024-12-20 CN disclosed
CN-111777593-B Novel compounds as inhibitors of rearrangement kinase during transfection 南京天印健华医药科技有限公司 2024-07-23 CN disclosed
EP-0027891-A1 Ammonium salts, a process for the preparation of amines underlying these, and coating compositions on the basis of manufactured polyurethane or epoxy resin products which contain the ammonium salts BAYER AG (DE) 1981-05-06 EP disclosed
US-4242355-A Novel 3-(aminoethyl)-phenols ROUSSEL UCLAF (FR) 1980-12-30 US disclosed
US-4218238-A Herbicidal 1-alkyl-3-phenylpyridinium salts ELI LILLY AND COMPANY (US) 1980-08-19 US disclosed
EP-0006359-A1 Use of 1-alkyl-3-phenylpyridinium salts as herbicides and herbicidal formulations containing the salts ELI LILLY AND COMPANY (US) 1980-01-09 EP disclosed
US-4174209-A Herbicidal 1-alkyl-3-phenylpyridinium salts ELI LILLY AND COMPANY (US) 1979-11-13 US disclosed
US-4089684-A EXPOSURE, POLYMERIC FILM, LATENT IMAGES, DEVELOPMENT, FROSTING, CHARGE TRANSFER XEROX CORPORATION (US) 1978-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR LMNA 2511/4885CYP3A4 447/4885ALDH1A1 4757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.