Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 11/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872322 | 0.95 | BDKRB1 (0.55) | BDKRB1LTB4R2ALDH1A1MEN1KMT2A | |
| SCHEMBL8873215 | 0.86 | BDKRB1 (0.41) | BDKRB1ALDH1A1BRS3 | |
| SCHEMBL8873832 | 0.85 | BDKRB1 (0.48) | BDKRB1LTB4R2 | |
| SCHEMBL8872745 | 0.83 | BDKRB1 (0.49) | BDKRB1LTB4R2ALDH1A1MEN1KMT2A | |
| SCHEMBL8873289 | 0.80 | BDKRB1 (0.49) | BDKRB1LTB4R2ALDH1A1MEN1KMT2A | |
| SCHEMBL8958440 | 0.79 | BDKRB1 (0.50) | BDKRB1LTB4R2ALDH1A1MEN1KMT2A | |
| SCHEMBL8872358 | 0.72 | BDKRB1 (0.38) | BDKRB1ALDH1A1BRS3 | |
| SCHEMBL6106685 | 0.72 | SMN1; SMN2 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8872353 | 0.71 | SLC6A3 (0.40) | BDKRB1ALDH1A1 | |
| SCHEMBL8872739 | 0.71 | LTB4R2 (0.52) | BDKRB1LTB4R2BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618969-A | Intermediates for imidazopyridines | EISAI CO., LTD. (JP) | 1997-04-08 | — | — | US | disclosed |
| US-5587504-A | Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates | EISAI CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5583229-A | Process for the preparation of imidazopyridine derivatives | EISAI CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |