Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 8/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872745 | 0.95 | BDKRB1 (0.49) | BDKRB1LTB4R2ALDH1A1AGTR1AGTR2 | |
| SCHEMBL8873289 | 0.87 | BDKRB1 (0.49) | BDKRB1LTB4R2ALDH1A1AGTR1AGTR2 | |
| SCHEMBL8873138 | 0.85 | SLC6A3 (0.39) | BDKRB1ALDH1A1SLC6A3 | |
| SCHEMBL8872322 | 0.84 | BDKRB1 (0.55) | BDKRB1LTB4R2ALDH1A1AGTR1AGTR2 | |
| SCHEMBL8873832 | 0.82 | BDKRB1 (0.48) | BDKRB1LTB4R2AGTR1AGTR2SLC6A3 | |
| SCHEMBL8873040 | 0.79 | BDKRB1 (0.54) | BDKRB1LTB4R2ALDH1A1MEN1KMT2A | |
| SCHEMBL8872577 | 0.76 | LTB4R2 (0.59) | LTB4R2AGTR1 | |
| SCHEMBL8872353 | 0.75 | SLC6A3 (0.40) | BDKRB1ALDH1A1AGTR1AGTR2SLC6A3 | |
| SCHEMBL8874082 | 0.74 | BDKRB1 (0.64) | BDKRB1LTB4R2ALDH1A1AGTR1AGTR2 | |
| SCHEMBL8872358 | 0.73 | BDKRB1 (0.38) | BDKRB1ALDH1A1AGTR1AGTR2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587504-A | Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates | EISAI CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |