Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 11/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872353 | 0.90 | SLC6A3 (0.40) | SLC6A3BDKRB1SLC6A4KDM4EALDH1A1 | |
| SCHEMBL8872358 | 0.87 | BDKRB1 (0.38) | SLC6A3BDKRB1SLC6A4KDM4EALDH1A1 | |
| SCHEMBL8872745 | 0.86 | BDKRB1 (0.49) | SLC6A3BDKRB1SLC6A4ALDH1A1 | |
| SCHEMBL8958440 | 0.85 | BDKRB1 (0.50) | SLC6A3BDKRB1ALDH1A1 | |
| SCHEMBL8873215 | 0.84 | BDKRB1 (0.41) | SLC6A3BDKRB1SLC6A4KDM4EALDH1A1 | |
| SCHEMBL8879293 | 0.76 | SLC6A3 (0.38) | SLC6A3BDKRB1SLC6A4ALDH1A1SLC6A2 | |
| SCHEMBL8872596 | 0.75 | LTB4R2 (0.42) | SLC6A3BDKRB1SLC6A4KDM4EALDH1A1 | |
| SCHEMBL8873832 | 0.74 | BDKRB1 (0.48) | SLC6A3BDKRB1SLC6A4SLC6A2 | |
| SCHEMBL8873901 | 0.73 | BDKRB1 (0.50) | SLC6A3BDKRB1SLC6A4KDM4EALDH1A1 | |
| SCHEMBL8873086 | 0.73 | BDKRB1 (0.54) | SLC6A3BDKRB1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618969-A | Intermediates for imidazopyridines | EISAI CO., LTD. (JP) | 1997-04-08 | — | — | US | disclosed |
| US-5587504-A | Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates | EISAI CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5583229-A | Process for the preparation of imidazopyridine derivatives | EISAI CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5557002-A | Process for the preparation of biphenyl containing intermediates useful in making angiotensin II receptor antagonists | EISAI CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |