Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873058 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8873056 | 0.99 | KDM4E (0.60) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8873061 | 0.99 | KDM4E (0.60) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL8872439 | 0.90 | — | — | |
| SCHEMBL8872447 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL8871876 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL8871872 | 0.89 | — | — | |
| SCHEMBL7917554 | 0.87 | KDM4E (0.61) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL7917547 | 0.87 | KDM4E (0.61) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL7917561 | 0.83 | KDM4E (0.59) | ALDH1A1KDM4EHTR7HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604242-A | ALKOXY- AND CARBOXY-SUBSTITUTED PIPERIDINES FOR SUPPRESSING UPTAKE OF GAMMA-AMINOBUTYRIC ACID, ANALGESICS, ANXIOLYTIC OR ANTIEPILEPTIC AGENTS | NOVO NORDISK A/S (DK) | 1997-02-18 | — | — | US | disclosed |
| EP-0705248-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000486-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1995-01-05 | — | — | WO | disclosed |