Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917547 | 1.00 | KDM4E (0.61) | KDM4EALDH1A1HTR7HTR1ADRD2 | |
| SCHEMBL7917559 | 0.96 | KDM4E (0.59) | KDM4EALDH1A1HTR7HTR1ADRD2 | |
| SCHEMBL7917561 | 0.96 | KDM4E (0.59) | KDM4EALDH1A1HTR7HTR1ADRD2 | |
| SCHEMBL7917293 | 0.89 | KDM4E (0.62) | KDM4EALDH1A1HTR7HTR1ADRD2 | |
| SCHEMBL7917296 | 0.89 | KDM4E (0.62) | KDM4EALDH1A1HTR7HTR1ADRD2 | |
| SCHEMBL7923206 | 0.87 | SLC6A1 (0.63) | — | |
| SCHEMBL7923211 | 0.87 | SLC6A1 (0.63) | — | |
| SCHEMBL8873244 | 0.87 | ALDH1A1 (0.61) | KDM4EALDH1A1HTR7HTR1ADRD2 | |
| SCHEMBL8873058 | 0.87 | ALDH1A1 (0.61) | KDM4EALDH1A1HTR7HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL7928865 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174898-B1 | TREATING FILARIAE IN LYMPHATIC SYSTEM BY ADMINISTERING N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS IN WHICH A SUBSTITUTED ALKYL CHAIN FORMS PART OF N-SUBSTITUENT AND SALTS | NOVO NORDISK A/S (DK) | 2001-01-16 | — | — | US | claimed |
| US-6174898-B1 | TREATING FILARIAE IN LYMPHATIC SYSTEM BY ADMINISTERING N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS IN WHICH A SUBSTITUTED ALKYL CHAIN FORMS PART OF N-SUBSTITUENT AND SALTS | NOVO NORDISK A/S (DK) | 2001-01-16 | — | — | US | disclosed |
| EP-0502031-B1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND A PHARMACEUTICAL COMPOSITION | NOVO NORDISK AS (DK) | 1997-08-20 | — | — | EP | disclosed |
| US-5198451-A | Treatment of epilepsy, inhibitors of gamma-aminobutyric acid uptake from synaptic cleft | NOVO NORDISK A/S (DK) | 1993-03-30 | — | — | US | disclosed |