Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | BACE1 | P56817 | 4/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873941 | 0.90 | MEN1 (0.46) | MEN1KMT2ACHRM4POLBACHE | |
| SCHEMBL8875798 | 0.82 | CHRM4 (0.41) | MEN1KMT2ACHRM4POLBACHE | |
| SCHEMBL5805867 | 0.82 | MEN1 (0.50) | MEN1KMT2ACHRM4POLBACHE | |
| SCHEMBL8873598 | 0.81 | MEN1 (0.46) | MEN1KMT2ACHRM4POLBACHE | |
| SCHEMBL8545147 | 0.81 | TACR1 (0.43) | MEN1KMT2ACHRM4POLBACHE | |
| SCHEMBL8874205 | 0.80 | CHRM4 (0.42) | MEN1KMT2ACHRM4ACHEFUCA1 | |
| SCHEMBL8875275 | 0.76 | CHRM4 (0.40) | MEN1KMT2ACHRM4POLBACHE | |
| SCHEMBL8873365 | 0.76 | TACR1 (0.46) | MEN1KMT2ACHRM4POLBACHE | |
| SCHEMBL8684093 | 0.74 | CHRM4 (0.41) | MEN1KMT2ACHRM4POLBACHE | |
| SCHEMBL8874651 | 0.72 | SIGMAR1 (0.46) | KMT2ACHRM4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624950-A | USEFUL IN TREATMENT OF ANALGESIA, INFLAMMATION, ASTHMA, ALLERGIES, CENTRAL NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS, IMMUNE SYSTEM DISORDERS, ANTISPASMODIC AGENTS, ANTIEMETIC AGENTS | RHONE-POULENC RORER S.A. (FR) | 1997-04-29 | — | — | US | disclosed |