Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MARK4 | Q96L34 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25414634 | 0.83 | KMT2A (0.74) | KMT2ARAB9AALDH1A1NPC1MEN1 | |
| SCHEMBL8873874 | 0.81 | NPC1 (0.71) | RAB9AALDH1A1NPC1SMN1; SMN2MARK4 | |
| SCHEMBL973109 | 0.80 | NPC1 (0.64) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL22342514 | 0.79 | ALDH1A1 (0.54) | KMT2ARAB9AALDH1A1NPC1MEN1 | |
| SCHEMBL15825411 | 0.78 | ALDH1A1 (0.62) | KMT2ARAB9AALDH1A1NPC1MEN1 | |
| SCHEMBL18221717 | 0.78 | NPC1 (0.63) | RAB9AALDH1A1NPC1SMN1; SMN2MARK4 | |
| SCHEMBL28669282 | 0.78 | KDM4E (0.58) | KMT2ARAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL8874527 | 0.78 | PTGS2 (0.57) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL19314578 | 0.78 | NPC1 (0.59) | KMT2ARAB9AALDH1A1NPC1MEN1 | |
| SCHEMBL1428632 | 0.77 | NPC1 (0.55) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658857-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | claimed |
| EP-0683779-A1 | IMIDAZOAZINES | BAYER AG (DE) | 1995-11-29 | — | — | EP | claimed |
| WO-1994018198-A1 | IMIDAZOAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-18 | — | — | WO | claimed |
| US-5658857-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |
| EP-0683779-A1 | IMIDAZOAZINES | BAYER AG (DE) | 1995-11-29 | — | — | EP | disclosed |
| WO-1994018198-A1 | IMIDAZOAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-18 | — | — | WO | disclosed |