Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 6/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596737 | 1.00 | TYRO3 (0.40) | TYRO3NTRK2CLK4DYRK1BMETAP1 | |
| SCHEMBL8596739 | 1.00 | TYRO3 (0.40) | TYRO3NTRK2CLK4DYRK1BMETAP1 | |
| SCHEMBL8873394 | 0.85 | TYRO3 (0.43) | TYRO3NTRK2CLK4DYRK1BMETAP1 | |
| SCHEMBL8594813 | 0.85 | TYRO3 (0.43) | TYRO3NTRK2CLK4DYRK1BMETAP1 | |
| SCHEMBL8873256 | 0.82 | METAP1 (0.58) | METAP1ACHECYP19A1 | |
| SCHEMBL8873267 | 0.82 | METAP1 (0.58) | METAP1ACHECYP19A1 | |
| SCHEMBL8873261 | 0.82 | METAP1 (0.58) | METAP1ACHECYP19A1 | |
| SCHEMBL8873299 | 0.81 | METAP1 (0.59) | METAP1ACHE | |
| SCHEMBL8595392 | 0.81 | METAP1 (0.59) | METAP1ACHE | |
| SCHEMBL8595390 | 0.81 | METAP1 (0.59) | METAP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646173-A | ANTISEROTONINE AGENTS; CENTRAL NERVOUS SYSTEM DISORDERS; ANTIDEPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1997-07-08 | — | — | US | disclosed |