Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 2/20 | 0.45 |
| ▸ | RARG | P13631 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8839085 | 0.81 | RARA (0.48) | RARARARBRARGNR1H4EPHX2 | |
| SCHEMBL8874249 | 0.79 | MAPT (0.48) | RARARARBRARGNR1H4EPHX2 | |
| SCHEMBL9285428 | 0.78 | RARA (0.50) | RARARARBRARGNR1H4EPHX2 | |
| SCHEMBL5027170 | 0.74 | MAPT (0.58) | RARARARBRARGWDR5ALDH1A1 | |
| SCHEMBL10204755 | 0.73 | CYP3A4 (0.47) | RARARARBRARGNR1H4EPHX2 | |
| SCHEMBL14453806 | 0.72 | KMT2A (0.50) | NR1H4EPHX2ALDH1A1MAPTCA1 | |
| SCHEMBL7940070 | 0.72 | RARA (0.49) | RARARARBRARGWDR5ALDH1A1 | |
| SCHEMBL8766130 | 0.72 | RARA (0.73) | RARARARBRARGNR1H4EPHX2 | |
| SCHEMBL8766137 | 0.72 | RARA (0.73) | RARARARBRARGNR1H4EPHX2 | |
| SCHEMBL8839343 | 0.72 | MEN1 (0.56) | RARARARBRARGALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597839-A | TREATMENT OF SKIN DISORDERS OR ANTIINFLAMMATORY AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-01-28 | — | — | US | disclosed |