Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 2/20 | 0.46 |
| ▸ | RARB | P10826 | 2/20 | 0.46 |
| ▸ | RARG | P13631 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8839085 | 0.88 | RARA (0.48) | MAPTNPC1RAB9ASMN1; SMN2RARA | |
| SCHEMBL7940070 | 0.84 | RARA (0.49) | MAPTSMN1; SMN2RARARARBRARG | |
| SCHEMBL9285428 | 0.80 | RARA (0.50) | MAPTNPC1SMN1; SMN2RARARARB | |
| SCHEMBL21376220 | 0.79 | HSD17B2 (0.61) | MAPTNPC1RAB9ASMN1; SMN2RARA | |
| SCHEMBL8874247 | 0.79 | RARA (0.45) | MAPTRARARARBRARGTSHR | |
| SCHEMBL8839343 | 0.79 | MEN1 (0.56) | MAPTNPC1RAB9ASMN1; SMN2RARA | |
| SCHEMBL5081222 | 0.78 | RARA (0.57) | NPC1RAB9ASMN1; SMN2RARARARB | |
| SCHEMBL8839378 | 0.78 | RARA (0.48) | MAPTNPC1RAB9ASMN1; SMN2RARA | |
| SCHEMBL8839128 | 0.78 | SMN1; SMN2 (0.54) | MAPTNPC1RAB9ASMN1; SMN2RARA | |
| SCHEMBL8839075 | 0.77 | RARA (0.44) | MAPTNPC1RAB9ASMN1; SMN2RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597839-A | TREATMENT OF SKIN DISORDERS OR ANTIINFLAMMATORY AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-01-28 | — | — | US | disclosed |