Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874363 | 1.00 | RAB9A (0.49) | RAB9AHPGDALDH1A1GAAMAPT | |
| SCHEMBL9159810 | 0.88 | MAPT (0.43) | RAB9AHPGDALDH1A1GAAMAPT | |
| SCHEMBL9159798 | 0.88 | MAPT (0.43) | RAB9AHPGDALDH1A1GAAMAPT | |
| SCHEMBL15631944 | 0.86 | POLB (0.51) | HPGDALDH1A1GAALMNAKDM4E | |
| SCHEMBL15630892 | 0.86 | POLB (0.51) | HPGDALDH1A1GAALMNAKDM4E | |
| SCHEMBL10615659 | 0.86 | POLB (0.51) | HPGDALDH1A1GAALMNAKDM4E | |
| SCHEMBL2325747 | 0.84 | KMT2A (0.47) | RAB9AHPGDALDH1A1GAAMAPT | |
| SCHEMBL7587366 | 0.84 | KMT2A (0.47) | RAB9AHPGDALDH1A1GAAMAPT | |
| SCHEMBL2081536 | 0.84 | KMT2A (0.47) | RAB9AHPGDALDH1A1GAAMAPT | |
| SCHEMBL10867412 | 0.82 | MMP9 (0.50) | ALDH1A1LMNASMN1; SMN2KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500811-A | Covalent RAS inhibitors and uses thereof | 锐新医药公司 | 2024-02-02 | — | — | CN | disclosed |
| US-5610153-A | ENZYME INHIBITORS; TREATMENT OF VASCULAR PROLIFERATION DISORDERS, STERILITY DYSFUNCTION, DYSMENORRHEA | CIBA-GEIGY CORPORATION (US) | 1997-03-11 | — | — | US | disclosed |