Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 2/20 | 0.41 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | GPR39 | O43194 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794576 | 0.84 | CBFB (0.43) | CBFBRUNX1GRM5SCN9AGPR39 | |
| SCHEMBL8315603 | 0.80 | CBFB (0.42) | CBFBRUNX1GRM5SCN9AGPR39 | |
| SCHEMBL8796995 | 0.78 | CBFB (0.39) | CBFBRUNX1GRM5SCN9AGPR39 | |
| SCHEMBL8798384 | 0.78 | CBFB (0.37) | CBFBRUNX1GRM5SCN9AGPR39 | |
| SCHEMBL9475647 | 0.77 | CBFB (0.43) | CBFBRUNX1GRM5SCN9AGPR39 | |
| SCHEMBL8795216 | 0.71 | TRPV1 (0.41) | CBFBRUNX1GRM5GPR39HCRTR1 | |
| SCHEMBL8796181 | 0.70 | GRM4 (0.35) | CBFBCYP2D6CYP3A4BACE1CTSD | |
| SCHEMBL9381836 | 0.69 | PSEN1 (0.36) | CBFBRUNX1TLR7ABL1PSEN1 | |
| SCHEMBL8795032 | 0.69 | PSEN1 (0.36) | CBFBRUNX1SCN9AABL1PSEN1 | |
| SCHEMBL7291317 | 0.68 | TRPV1 (0.36) | TRPV1CYP2D6CYP3A4BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602152-A | POTASSIUM CHANNEL MODULATOR | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-02-11 | — | — | US | disclosed |