Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 11/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.43 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.43 |
| ▸ | ATG7 | O95352 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10022901 | 1.00 | ADK (0.52) | ADKSLC29A1PRMT5METTL3ATG7 | |
| SCHEMBL29720474 | 0.89 | ADK (0.52) | ADKPRMT5METTL3ATG7CA2 | |
| SCHEMBL19603993 | 0.88 | ADK (0.47) | ADKSLC29A1PRMT5METTL3 | |
| SCHEMBL10178145 | 0.88 | ADK (0.47) | ADKSLC29A1PRMT5METTL3 | |
| SCHEMBL10022900 | 0.84 | ADK (0.44) | ADKSLC29A1PRMT5METTL3 | |
| SCHEMBL887503 | 0.84 | ADK (0.44) | ADKSLC29A1PRMT5METTL3 | |
| SCHEMBL887477 | 0.83 | ADK (0.65) | ADKSLC29A1HIF1A | |
| SCHEMBL10022899 | 0.83 | ADK (0.65) | ADKSLC29A1HIF1A | |
| SCHEMBL23734183 | 0.83 | PRMT5 (0.36) | ADKPRMT5METTL3ATG7HIF1A | |
| SCHEMBL23734375 | 0.83 | PRMT5 (0.36) | ADKPRMT5METTL3ATG7HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000801-B2 | Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-06-19 | — | — | US | disclosed |
| US-10000801-B2 | Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-06-19 | — | — | US | disclosed |
| US-20170114403-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-04-27 | — | — | US | disclosed |
| US-20170114403-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-04-27 | — | — | US | disclosed |
| US-9528151-B2 | Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-12-27 | — | — | US | disclosed |
| US-20140315191-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-10-23 | — | — | US | disclosed |
| US-20130280700-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2013-10-24 | — | — | US | disclosed |
| US-7883869-B2 | for sequencing single-stranded DNA by employing a nanopore and modified nucleotides | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2011-02-08 | — | — | US | disclosed |
| US-20100092952-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-04-15 | — | — | US | disclosed |