Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.36 |
| ▸ | ADK | P55263 | 6/20 | 0.35 |
| ▸ | ATG7 | O95352 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23734183 | 1.00 | PRMT5 (0.36) | PRMT5METTL3ADKATG7CA2 | |
| SCHEMBL23734520 | 0.89 | ADK (0.33) | ADK | |
| SCHEMBL24823717 | 0.89 | ADK (0.33) | ADK | |
| SCHEMBL20810884 | 0.89 | ADK (0.38) | PRMT5METTL3ADKATG7CA2 | |
| SCHEMBL2611648 | 0.89 | ADK (0.38) | PRMT5METTL3ADKATG7CA2 | |
| SCHEMBL23734521 | 0.88 | ADK (0.31) | ADK | |
| SCHEMBL24823716 | 0.88 | ADK (0.31) | ADK | |
| SCHEMBL23734373 | 0.87 | ADK (0.34) | ADK | |
| SCHEMBL24824049 | 0.87 | ADK (0.34) | ADK | |
| SCHEMBL23734291 | 0.87 | ADK (0.30) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11085076-B2 | Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11085076-B2 | Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis | POLRMT, RNGTT, MTR | PRMT5 3345/4885METTL3 1962/4885ADK 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.