Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876623 | 1.00 | MAOB (0.40) | MAOBS1PR5S1PR1S1PR3ANO1 | |
| SCHEMBL9217974 | 1.00 | MAOB (0.40) | MAOBS1PR5S1PR1S1PR3ANO1 | |
| SCHEMBL8876723 | 0.88 | MAOB (0.39) | MAOBS1PR5S1PR1S1PR3ANO1 | |
| SCHEMBL9490237 | 0.81 | HTR6 (0.53) | MAOBHTR6HIF1AHPGDSMN1; SMN2 | |
| SCHEMBL9216132 | 0.81 | S1PR5 (0.47) | S1PR5S1PR1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL8836583 | 0.77 | PPARG (0.44) | MAOBS1PR5S1PR1 | |
| SCHEMBL8876644 | 0.77 | PPARG (0.44) | MAOBS1PR5S1PR1 | |
| SCHEMBL8836590 | 0.77 | PPARG (0.44) | MAOBS1PR5S1PR1 | |
| SCHEMBL9209731 | 0.75 | S1PR5 (0.43) | S1PR5S1PR1S1PR3 | |
| SCHEMBL9211970 | 0.75 | MAOB (0.53) | MAOBSCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663368-A | Synthesis of acid addition salts of hydroxylamines | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0708753-A4 | SYNTHESIS OF ACID ADDITION SALTS OF HYDROXYLAMINES | SMITHKLINE BEECHAM CORP (US) | 1996-10-02 | — | — | EP | disclosed |
| EP-0708753-A1 | SYNTHESIS OF ACID ADDITION SALTS OF HYDROXYLAMINES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002402-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-01-26 | — | — | WO | disclosed |
| WO-1995002574-A1 | SYNTHESIS OF ACID ADDITION SALTS OF HYDROXYLAMINES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-01-26 | — | — | WO | disclosed |