SCHEMBL88751

SCHEMBL88751

C=CCNc1ccnnn1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.39
KDM4E B2RXH2 6/20 0.39
HPGD P15428 3/20 0.39
HCAR3 P49019 1/20 0.39
SLC2A1 P11166 1/20 0.39
SMN1; SMN2 Q16637 5/20 0.37
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
CA14 Q9ULX7 1/20 0.34
RAB9A P51151 3/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 1/20 0.33
PDE10A Q9Y233 1/20 0.33
LMNA P02545 3/20 0.32
HTT P42858 3/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9346948 0.80 SMN1; SMN2 (0.41) ALDH1A1KDM4EHPGDHCAR3SMN1; SMN2
SCHEMBL7105415 0.78
SCHEMBL7174071 0.77 GOT1 (0.48) ALDH1A1KDM4EHPGDHCAR3SLC2A1
SCHEMBL10352061 0.77
SCHEMBL27565312 0.74
SCHEMBL5845138 0.74
SCHEMBL2586175 0.74
SCHEMBL27736222 0.71 GOT1 (0.32)
SCHEMBL4099219 0.71 KDM4E (0.40) ALDH1A1KDM4ESMN1; SMN2RAB9AMEN1
SCHEMBL4251072 0.70 NPC1 (0.35) ALDH1A1SMN1; SMN2RAB9AGAAGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4113947-A WASH RESISTANT WATER REPELLEMT FINISH FOR FIBERS CIBA-GEIGY CORPORATION (US) 1978-09-12 US claimed
EP-3617251-A1 THERMOPLASTIC COMPOSITION COMPRISING A POLYSILOXANE BEARING DIAMINOTRIAZINE MOIETIES RHODIA OPERATIONS (FR) 2020-03-04 EP disclosed
US-10407649-B2 Use in detergent compositions of polymers obtained by low-concentration reverse emulsion polymerization with a low content of neutralized monomers S.P.C.P. SA (FR) 2019-09-10 US disclosed
EP-2152839-B1 DETERGENT COMPOSITION WITH HYDROPHILIZING SOIL-RELEASE AGENT AND METHODS FOR USING SAME SOLVAY USA INC (US) 2018-11-14 EP disclosed
US-20170218308-A1 USE IN DETERGENT COMPOSITIONS OF POLYMERS OBTAINED BY LOW-CONCENTRATION REVERSE EMULSION POLYMERIZATION WITH A LOW CONTENT OF NEUTRALIZED MONOMERS S.P.C.M. SA (FR) 2017-08-03 US disclosed
EP-3177703-A1 USE IN DETERGENT COMPOSITIONS OF POLYMERS OBTAINED BY LOW-CONCENTRATION, INVERSE EMULSION POLYMERIZATION WITH A LOW CONTENT OF NEUTRALIZED MONOMERS S.P.C.M. SA (FR) 2017-06-14 EP disclosed
WO-2016020622-A1 USE IN DETERGENT COMPOSITIONS OF POLYMERS OBTAINED BY LOW-CONCENTRATION, INVERSE EMULSION POLYMERIZATION WITH A LOW CONTENT OF NEUTRALIZED MONOMERS S.P.C.M. SA (FR) 2016-02-11 WO disclosed
US-9044413-B2 Block polymers, compositions and methods for use for foams, laundry detergents, and shower rinses and coagulants SOLVAY USA INC. (US) 2015-06-02 US disclosed
US-8987169-B2 Stabilized herbicidal composition BAYER CROPSCIENCE LP (US) 2015-03-24 US disclosed
US-8907033-B2 Polymers, compositions and methods of use for foams, laundry detergents, shower rinses and coagulants SOLVAY USA INC. (US) 2014-12-09 US disclosed
EP-0010247-B1 PHOSPHATE-FREE WASHING AGENT AND PROCESS FOR ITS PRODUCTION Henkel Kommanditgesellschaft auf Aktien (DE) 1983-03-23 EP disclosed
US-4264480-A Stable aqueous suspension of water-insoluble, calcium-binding aluminosilicates and organic suspending agents HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1981-04-28 US disclosed
EP-0010247-A1 Phosphate-free washing agent and process for its production Henkel Kommanditgesellschaft auf Aktien (DE) 1980-04-30 EP disclosed
US-4179391-A ALUMINOSILICATES, SURFACTANTS, PHOSPHONIC ACIDS AND SALTS THEREOF, PERBORATE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1979-12-18 US disclosed
US-4179393-A HYDROXYALKYL AMINE OR ETHYLENE OR PROPYLENE OXIDE ADDUCTS WITH A DAMINE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1979-12-18 US disclosed
US-4171278-A WITH AN ANIONIC SULFATE OR SULFONATE OR A NONIONIC ETHOXYLATE TYPE SURFACTANT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1979-10-16 US disclosed
US-4169074-A Compositions for cold water washing containing N-substituted ω-hydroxyalkane carboxylic acid amides HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1979-09-25 US disclosed
US-4150024-A Reaction products of epsilon-caprolactam with vicinal hydroxyalkylamines and alkoxylation products thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1979-04-17 US disclosed
US-4054739-A Process for the substitution of chlorine atoms of cyanuric chloride DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-10-18 US disclosed
US-3985670-A Liquid regulated-foam detergent compositions HENKEL & CIE G.M.B.H. (DT) 1976-10-12 US disclosed